Article
Gastric adenocarcinoma of the fundic gland type shares common genetic and phenotypic features with pyloric gland adenoma.
Pathology international - 1 Jun 2013
Kushima Ryoji, Sekine Shigeki, Matsubara Akiko, Taniguchi Hirokazu, Ikegami Masahiro, Tsuda Hitoshi
Abstract excerpt
Gastric adenocarcinoma of the fundic gland type (GAFG) and pyloric gland adenoma (PGA) have recently been recognized as rare types of neoplasia. We performed comparative immunohistochemical and genetic analyses of 3 GAFGs and 12 PGAs. All of the 3 GAFGs were diffusely positive for pepsinogen-I, MIST1 and MUC6, indicating the predominantly chief cell/mucous neck cell differentiation of these tumors. A small number...
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