Article
Association between acute lymphoblastic leukemia and partial IgA deficiency in a young man--a family study.
Nouvelle revue francaise d'hematologie - 1 Jan 1990
Chevailler A, Ifrah N, Monteiro R C, Keyeux G, Renier G, Lefranc M P, Lesavre P, Hurez D
Abstract excerpt
We report on an unusual association between partial IgA deficiency and acute lymphoblastic leukemia in a young man. We also report results of the family study of immunoglobulin levels, sIgA B cells, in vitro IgA synthesis and molecular analysis of the structural C alpha genes. The IgA deficiency was present at diagnosis of leukemia prior to any therapy. The indirect arguments for a preexisting IgA deficiency are...
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