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Article

Monogenic diabetes: a gateway to precision medicine in diabetes.

The Journal of clinical investigation - 1 Feb 2021

Zhang Haichen, Colclough Kevin, Gloyn Anna L, Pollin Toni I

Abstract excerpt

Monogenic diabetes refers to diabetes mellitus (DM) caused by a mutation in a single gene and accounts for approximately 1%-5% of diabetes. Correct diagnosis is clinically critical for certain types of monogenic diabetes, since the appropriate treatment is determined by the etiology of the disease (e.g., oral sulfonylurea treatment of HNF1A/HNF4A-diabetes vs. insulin injections in type 1 diabetes). However,...

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Identifiers

PMID: 33529164
DOI: 10.1172/JCI142244
PMCID: PMC7843214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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