Article
Th1 cytokine gene polymorphism and the corresponding plasma cytokine levels: A comparative study in HIV-1 positive and exposed uninfected infants.
Journal of medical virology - 1 Feb 2022
R Chavan Vijay, Ahir Swati, Kerkar Shilpa, Ansari Zakia, Samant-Mavani Padmaja, Nanavati Ruchi, Mehta Preeti, Mania-Pramanik Jayanti
Abstract excerpt
The pro-inflammatory (Th1) cytokines namely interleukin (IL)-2, IL-6, IL-12, interferon (IFN)-γ, tumor necrosis factor-α (TNF-α) are vital in the clearance of HIV infection. This prospective cohort study aimed to evaluate the polymorphisms of Th1 cytokine genes and their corresponding plasma cytokine levels in HIV-1 positive and exposed uninfected (EU) infants born to HIV-1 positive mothers. CD4 count, viral load...
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