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Article

Mutation in spike protein cleavage site and pathogenesis of feline coronavirus.

Emerging infectious diseases - 1 Jul 2013

Licitra Beth N, Millet Jean K, Regan Andrew D, Hamilton Brian S, Rinaldi Vera D, Duhamel Gerald E, Whittaker Gary R

Abstract excerpt

Feline coronaviruses (FCoV) exist as 2 biotypes: feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV). FECV causes subclinical infections; FIPV causes feline infectious peritonitis (FIP), a systemic and fatal disease. It is thought that mutations in FECV enable infection of macrophages, causing FIP. However, the molecular basis for this biotype switch is unknown. We examined a furin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spike Glycoprotein, Coronavirus

Source

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Identifiers

PMID: 23763835
DOI: 10.3201/eid1907.121094
PMCID: PMC3713968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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