Article
The effect of antineoplastic drugs in a male spontaneous mammary tumor model.
PloS one - 1 Jan 2014
Shishido Stephanie N, Faulkner Emma B, Beck Amanda, Nguyen Thu A
Abstract excerpt
Male breast cancer is a rare disease. The limited number of clinical cases has led to the primary treatments for men being derived from female breast cancer studies. Here the transgenic strain FVB/N-Tg(MMTV-PyVT)634Mul/J (also known as PyVT) was used as a model system for measuring tumor burden and drug sensitivity of the antineoplastic drugs tamoxifen, cisplatin, and paclitaxel on tumorigenesis at an early stage...
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