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Article

Mapping the binding region on the low density lipoprotein receptor for blood coagulation factor VIII.

The Journal of biological chemistry - 26 Jul 2013

Kurasawa James H, Shestopal Svetlana A, Karnaukhova Elena, Struble Evi B, Lee Timothy K, Sarafanov Andrey G

Abstract excerpt

Low density lipoprotein receptor (LDLR) was shown to mediate clearance of blood coagulation factor VIII (FVIII) from the circulation. To elucidate the mechanism of interaction of LDLR and FVIII, our objective was to identify the region of the receptor necessary for binding FVIII. Using surface pl...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23754288
DOI: 10.1074/jbc.M113.468108
PMCID: PMC3724656

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23754288-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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