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Article

Storage Conditions and Stability of Global DNA Methylation in Placental Tissue

1 Jun 2013

Abstract excerpt

AIM: The placenta is an informative and easily available tissue for many epidemiological studies. We analyzed the extent to which storage delay affects DNA methylation. MATERIAL & METHODS: Biopsies from two placentas were sequentially stored at -80°C after standing at room temperature for 30 min, 1 h, 2 h, 6 h and 24 h. Global DNA methylation was measured by bisulfite pyrosequencing of repetitive elements and the...

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Share to Epigenetics and DNA Methylation
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PMID: 23750648
DOI: 10.2217/epi.13.29

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