Article
Serum hepcidin and growth differentiation factor-15 (GDF-15) levels in polycythemia vera and essential thrombocythemia.
European journal of haematology - 1 Sept 2013
Tarkun Pinar, Mehtap Ozgur, Atesoğlu Elif B, Geduk Ayfer, Musul Mahmut M, Hacihanefioglu Abdullah
Abstract excerpt
OBJECTIVES: Hepcidin plays a regulatory role in systemic iron homeostasis. GDF-15 has been found to be expressed from matured erythroblasts and very high levels of GDF-15 suppresses hepcidin secretion. In this study, we evaluated hepcidin and GDF-15 levels in polycythemia vera (PV) and essential thrombocythemia (ET). METHODS: The study included 29 patients and 21 healthy controls. The patient group included 13...
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