Article
Epidemiologic and clinical characteristics of nontransfusion-dependent thalassemia in the United States.
Pediatric blood & cancer - 1 Jul 2018
Vichinsky Elliott, Cohen Alan, Thompson Alexis A, Giardina Patricia J, Lal Ashutosh, Paley Carole, Cheng Wendy Y, McCormick Nora, Sasane Medha, Qiu Ying, Kwiatkowski Janet L
Abstract excerpt
BACKGROUND: Nontransfusion-dependent thalassemia (NTDT) refers to a diverse group of thalassemia mutations and clinical phenotypes that do not require chronic transfusions. It is increasingly prevalent in the United States. PROCEDURE: This study reviews the epidemiology and clinical characteristics of 138 patients with NTDT treated at four US thalassemia centers from 1997 to 2014. Data on laboratory results,...
Topics
- Adolescent
- Adult
- Aged
- Child
- Child, Preschool
- Female
- Genotype
- Humans
- Infant
- Infant, Newborn
- Male