Article
Sensitive and specific detection of mosaic chromosomal abnormalities using the Parent-of-Origin-based Detection (POD) method.
BMC genomics - 31 May 2013
Baugher Joseph D, Baugher Benjamin D, Shirley Matthew D, Pevsner Jonathan
Abstract excerpt
BACKGROUND: Mosaic somatic alterations are present in all multi-cellular organisms, but the physiological effects of low-level mosaicism are largely unknown. Most mosaic alterations remain undetectable with current analytical approaches, although the presence of such alterations is increasingly implicated as causative for disease. RESULTS: Here, we present the Parent-of-Origin-based Detection (POD) method for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.