Article
Epistatic interaction of Arg72Pro TP53 and -710 C/T VEGFR1 polymorphisms in breast cancer: predisposition and survival.
Molecular and cellular biochemistry - 1 Jul 2013
Rodrigues Patricia, Furriol Jessica, Tormo Eduardo, Ballester Sandra, Lluch Ana, Eroles Pilar
Abstract excerpt
The tumour-suppressor gene TP53 has been associated with the angiogenic pathway by a TP53 response element sequence of the VEGFR1 promoter. Within that sequence, the polymorphism -710 C/T VEGFR1, which confers variable transcriptional activation by TP53, has been identified. Our group found an as...
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