Article
Influence of CYP2C8*2 on the pharmacokinetics of pioglitazone in healthy African-American volunteers.
Pharmacotherapy - 1 Sept 2013
Aquilante Christina L, Wempe Michael F, Spencer Samantha H, Kosmiski Lisa A, Predhomme Julie A, Sidhom Maha S
Abstract excerpt
STUDY OBJECTIVES: To determine the influence of the Cytochrome P450 (CYP) 2C8*2 polymorphism on pioglitazone pharmacokinetics in healthy African-American volunteers. DESIGN: Prospective, open-label, single-dose pharmacokinetic study. SETTING: University of Colorado Hospital Clinical and Translational Research Center. PARTICIPANTS: Healthy African-American volunteers between 21 and 60 years of age were enrolled in...
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