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Article

Role of epithelial sodium channels and their regulators in hypertension.

The Journal of biological chemistry - 1 Oct 2010

Soundararajan Rama, Pearce David, Hughey Rebecca P, Kleyman Thomas R

Abstract excerpt

The kidney has a central role in the regulation of blood pressure, in large part through its role in the regulated reabsorption of filtered Na(+). Epithelial Na(+) channels (ENaCs) are expressed in the most distal segments of the nephron and are a target of volume regulatory hormones. A variety o...

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Identifiers

PMID: 20624922
DOI: 10.1074/jbc.R110.155341
PMCID: PMC2945528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20624922-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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