Article
High expression of Sonic hedgehog signaling proteins is related to the favorable outcome, EGFR mutation, and lepidic predominant subtype in primary lung adenocarcinoma.
Annals of surgical oncology - 1 Dec 2013
Kim Ji Eun, Kim Hyojin, Choe Ji-Young, Sun Pingli, Jheon Sanghoon, Chung Jin-Haeng
Abstract excerpt
BACKGROUND: Dysregulation of the Sonic hedgehog (SHH) signaling pathway has been identified in many human malignancies. However, it remains unclear whether this pathway is activated in human lung adenocarcinoma. METHODS: We investigated the expression of the SHH ligand and its downstream molecule...
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