Article
A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations.
Nature genetics - 1 Jul 2013
Hu Zhibin, Shi Yongyong, Mo Xuming, Xu Jing, Zhao Bijun, Lin Yuan, Yang Shiwei, Xu Zhengfeng, Dai Juncheng, Pan Shandong, Da Min, Wang Xiaowei, Qian Bo, Wen Yang, Wen Juan, Xing Jinliang, Guo Xuejiang, Xia Yankai, Ma Hongxia, Jin Guangfu, Yu Shiqiang, Liu Jiayin, Zhou Zuomin, Wang Xinru, Chen Yijiang, Sha Jiahao, Shen Hongbing
Abstract excerpt
Congenital heart malformation (CHM) is the most common form of congenital human birth anomaly and is the leading cause of infant mortality. Although some causative genes have been identified, little progress has been made in identifying genes in which low-penetrance susceptibility variants occur in the majority of sporadic CHM cases. To identify common genetic variants associated with sporadic non-syndromic CHM...
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