Article
Identification of a conjunctivitis-associated gene locus from the virulence plasmid of Yersinia enterocolitica.
Infection and immunity - 1 Aug 1990
Miliotis M D, Morris J G, Cianciosi S, Wright A C, Wood P K, Robins-Browne R M
Abstract excerpt
The virulence plasmid (pYV) of Yersinia enterocolitica is necessary for production of conjunctivitis in guinea pigs and for mouse lethality. To identify the genes responsible for production of conjunctivitis in guinea pigs, we subcloned the BamHI and SalI restriction fragments of the virulence pl...
Topics
- Animals
- Bacterial Outer Membrane Proteins
- Chromosome Deletion
- Conjunctivitis, Bacterial
- Electrophoresis, Polyacrylamide Gel
- Female
- Guinea Pigs
- Liver
- Mice
- Mice, Inbred BALB C
- Mutation
- Plasmids
- Restriction Mapping
- Spleen
- Virulence
- Yersinia Infections
- Yersinia enterocolitica