Article
Identification of a conjunctivitis-associated gene locus from the virulence plasmid of Yersinia enterocolitica.
Infection and immunity - 1 Aug 1990
Miliotis M D, Morris J G, Cianciosi S, Wright A C, Wood P K, Robins-Browne R M
Abstract excerpt
The virulence plasmid (pYV) of Yersinia enterocolitica is necessary for production of conjunctivitis in guinea pigs and for mouse lethality. To identify the genes responsible for production of conjunctivitis in guinea pigs, we subcloned the BamHI and SalI restriction fragments of the virulence plasmid of Y. enterocolitica A2635 (serotype O:8) into derivatives of the broad-host-range plasmid pRK290 and introduced...
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