Article
Coalescent tree imbalance and a simple test for selective sweeps based on microsatellite variation.
PLoS computational biology - 1 Jan 2013
Li Haipeng, Wiehe Thomas
Abstract excerpt
Selective sweeps are at the core of adaptive evolution. We study how the shape of coalescent trees is affected by recent selective sweeps. To do so we define a coarse-grained measure of tree topology. This measure has appealing analytical properties, its distribution is derived from a uniform, and it is easy to estimate from experimental data. We show how it can be cast into a test for recent selective sweeps...
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