Article
Characterization of proposed human B-1 cells reveals pre-plasmablast phenotype.
Blood - 27 Jun 2013
Covens Kris, Verbinnen Bert, Geukens Nick, Meyts Isabelle, Schuit Frans, Van Lommel Leentje, Jacquemin Marc, Bossuyt Xavier
Abstract excerpt
Controversy has arisen about the nature of circulating human CD20(+)CD27(+)CD43(+)CD70(-)CD69(-) B cells. Although originally described as being the human counterpart of murine B-1 B cells, some studies have raised the possibility that these might instead be plasmablasts. In this article, we have further characterized the putative B-1 cells and compared them directly with memory B cells and plasmablasts for...
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