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Article

IL28B minor allele is associated with a younger age of onset of hepatocellular carcinoma in patients with chronic hepatitis C virus infection.

Journal of gastroenterology - 1 Apr 2014

Sato Masaya, Kato Naoya, Tateishi Ryosuke, Muroyama Ryosuke, Kowatari Norie, Li Wenwen, Goto Kaku, Otsuka Motoyuki, Shiina Shuichiro, Yoshida Haruhiko, Omata Masao, Koike Kazuhiko

Abstract excerpt

BACKGROUND: IL28B polymorphisms were shown to be associated with a response to peg-interferon-based treatment in chronic hepatitis C (CHC) and spontaneous clearance. However, little is known about how this polymorphism affects the course of CHC, including the development of hepatocellular carcinoma (HCC). We evaluated the influence of IL28B polymorphisms on hepatocarcinogenesis in CHC patients. METHODS: We...

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PMID: 23689989
DOI: 10.1007/s00535-013-0826-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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