Altered <scp>mRNA</scp> and protein expression of filaggrin in the skin of a canine animal model for atopic dermatitis

Abstract excerpt

BACKGROUND: Filaggrin is a structural protein that has attracted increasing interest over the past decade for its role in the pathogenesis of human atopic dermatitis (AD). Null mutations in its sequence are considered risk factors in the development of AD. HYPOTHESIS/OBJECTIVES: To investigate canine filaggrin mRNA and protein expression in the skin of atopic beagles with experimentally induced AD compared with...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Allergic Rhinitis and Sensitization
• Share to Dermatology and Skin Diseases
• Share to Mast cells and histamine