Article
A stepwise α-thalassemia screening strategy in high-prevalence areas.
European journal of haematology - 1 Aug 2013
Alkindi Salam S, Alzadjali Shoaib, Daar Shahina, Sindhuvi Eunice, Wali Yasser, Pathare Anil V, Venugopal Suresh, Lapoumeroulie Claudine, Srivastava Alok, Krishnamoorthy Rajagopal
Abstract excerpt
INTRODUCTION: Coinheritance of α-thalassemia influences the clinical and hematological phenotypes of β-hemoglobinopathies (β-thalassemia and sickle cell disease) and when present together in significant frequency within a population, a spectrum of clinical forms is observed. Precise molecular characterization of α-thalassemia is important in understanding their disease-modifying role in β-hemoglobinopathies and...
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