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Article

Sendai virus transgene in a novel gene therapy for laryngotracheal disease

10 May 2013

Abstract excerpt

OBJECTIVES/HYPOTHESIS: Vocal cord scar formation and laryngotracheal stenosis (LTS) are challenging problems for otolaryngologists. Sendai virus (SeV) vectors have been shown to transduce airway epithelium efficiently, and are thus ideal for modulating airway wound-healing therapy. To assess the potential utility of SeV gene therapy for laryngotracheal diseases, we established a novel LTS model and examined the...

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PMID: 23666749
DOI: 10.1002/lary.23917

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