Article
Does congenital cytomegalovirus infection lead to hearing loss by inducing mutation of the GJB2 gene?
Pediatric research - 1 Aug 2013
Li Lu-Quan, Tan Jun-Jie, Zhou Yuan, Yu Jia-Lin
Abstract excerpt
BACKGROUND: Congenital cytomegalovirus (CMV) infection and mutation of the gap junction β-2 (GJB2) gene are important causes of sensorineural hearing loss (SNHL). This study aims to determine if congenital CMV infection leads to deafness by inducing GJB2 mutation. METHODS: GJB2 gene sequencing and auditory brainstem response testing were performed in 159 neonates (63 with and 96 without CMV infection) from August...
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