Article
Invariant natural killer T cells are enriched at the site of cutaneous inflammation in lupus erythematosus.
Journal of dermatological science - 1 Jul 2013
Hofmann Silke C, Bosma Anneleen, Bruckner-Tuderman Leena, Vukmanovic-Stejic Milica, Jury Elizabeth C, Isenberg David A, Mauri Claudia
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is associated with a numerical and functional reduction of peripheral blood (PB) invariant natural killer T (iNKT) cells. Limited information exists on the role of iNKT cells in the pathogenesis of lupus erythematosus. OBJECTIVE: To investigate the frequency and phenotype of iNKT cells in PB and dermal infiltrates from patients with SLE, subacute-cutaneous lupus...
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