Article
The benefits of selecting phenotype-specific variants for applications of mixed models in genomics.
Scientific reports - 1 Jan 2013
Lippert Christoph, Quon Gerald, Kang Eun Yong, Kadie Carl M, Listgarten Jennifer, Heckerman David
Abstract excerpt
Applications of linear mixed models (LMMs) to problems in genomics include phenotype prediction, correction for confounding in genome-wide association studies, estimation of narrow sense heritability, and testing sets of variants (e.g., rare variants) for association. In each of these application...
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