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Article

Localization of a locus for Charcot-Marie-Tooth neuropathy type Ia (CMT1A) to chromosome 17.

Genomics - 1 Jul 1990

McAlpine P J, Feasby T E, Hahn A F, Komarnicki L, James S, Guy C, Dixon M, Qayyum S, Wright J, Coopland G

Abstract excerpt

Phenotypic data for 71 genetic markers for members of five Caucasian kindreds were tested for linkage with the autosomal dominant mutations causing Charcot-Marie-Tooth (hereditary motor sensory) neuropathy type I, characterized by markedly reduced nerve conduction velocities. Lod score analysis gave no evidence of linkage to the closely linked chromosome 1 loci SPTA1-FY-F5-AT3 and APOA2. In contrast, these...

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Source

Identifiers

PMID: 2365358
DOI: 10.1016/0888-7543(90)90175-t

Genes

APOA2
MYH2
SPTA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Localization of a locus for Charcot-Marie-Tooth neuropathy type Ia (CMT1A) to chromosome 17.PMID 2365358Read ↗

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A second locus for an axonal form of autosomal recessive Charcot-Marie-Tooth disease maps to chromosome 19q13.3.Semantic proximity Read ↗

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