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Article

Fine localization of the CMT4A locus using a PAC contig and haplotype analysis.

Neurogenetics - 1 Dec 1998

Ben Othmane K, Rochelle J M, Ben Hamida M, Slotterbeck B, Rao N, Hentati F, Pericak-Vance M A, Vance J M

Abstract excerpt

Charcot-Marie-Tooth disease type 4A (CMT4A) is a severe, autosomal recessive peripheral neuropathy linked to chromosome 8q13-q21. We have previously constructed a YAC contig across the CMT4A region and narrowed the disease-flanking interval to approximately three megabases. Subsequently, we constructed a PAC/BAC contig made of 44 clones and mapped 44 new and 30 previous STSs, ESTs, and polymorphic makers to the...

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PMID: 9933296
DOI: 10.1007/s100480050047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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