Article
Human β-defensin-2 as a marker for disease severity and skin barrier properties in atopic dermatitis.
The British journal of dermatology - 1 Sept 2013
Clausen M-L, Jungersted J M, Andersen P S, Slotved H-C, Krogfelt K A, Agner T
Abstract excerpt
BACKGROUND: Skin infections related to disrupted antimicrobial defence are a common problem in atopic dermatitis (AD). Altered levels of antimicrobial peptides, including human β-defensin (hBD)-2, have been reported in AD skin, and a link to impaired barrier function has been suggested. OBJECTIVES: To study hBD-2 in relation to skin barrier function in patients with AD and controls, and to study hBD-2 in relation...
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