Article
The pvc operon regulates the expression of the Pseudomonas aeruginosa fimbrial chaperone/usher pathway (cup) genes.
PloS one - 1 Jan 2013
Qaisar Uzma, Luo Liming, Haley Cecily L, Brady Sean F, Carty Nancy L, Colmer-Hamood Jane A, Hamood Abdul N
Abstract excerpt
The Pseudomonas aeruginosa fimbrial structures encoded by the cup gene clusters (cupB and cupC) contribute to its attachment to abiotic surfaces and biofilm formation. The P. aeruginosa pvcABCD gene cluster encodes enzymes that synthesize a novel isonitrile functionalized cumarin, paerucumarin. Paerucumarin has already been characterized chemically, but this is the first report elucidating its role in bacterial...
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