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Article

Efavirenz intoxication due to a new CYP2B6 constellation.

Antiviral therapy - 1 Jan 2013

Anagnostopoulos Alexia, Rotger Margalida, Aouri Manel, Kuster Stefan P, Telenti Amalio, Décosterd Laurent A, Günthard Huldrych F

Abstract excerpt

Here, we describe severe neuropsychiatric symptoms in an HIV-positive Asian man with extremely high efavirenz plasma levels while receiving standard treatment with efavirenz/tenofovir/emtricitabine fixed-dose regimen. Genetic examination revealed compound homozygosity for loss-of-function alleles...

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Source

Identifiers

PMID: 23640958
DOI: 10.3851/IMP2571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23640958-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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