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Article

A shift in the dominant phenotype governs the pH-induced metabolic switch of Clostridium acetobutylicumin phosphate-limited continuous cultures.

Applied microbiology and biotechnology - 1 Jul 2013

Millat Thomas, Janssen Holger, Thorn Graeme J, King John R, Bahl Hubert, Fischer Ralf-Jörg, Wolkenhauer Olaf

Abstract excerpt

In response to changing extracellular pH levels, phosphate-limited continuous cultures of Clostridium acetobutylicum reversibly switches its metabolism from the dominant formation of acids to the prevalent production of solvents. Previous experimental and theoretical studies have revealed that th...

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PMID: 23640360
DOI: 10.1007/s00253-013-4860-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23640360-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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