Article
Helicobacter pylori‐induced alteration of epithelial cell signaling and polarity: A possible mechanism of gastric carcinoma etiology and disparity
29 Apr 2013
Abstract excerpt
Gastric cancer, a disease of disparity associated with Helicobacter pylori (H. pylori) infection, is the world's second leading cause of cancer deaths. The pathogen H. pylori target the epithelial adhesion receptors, E-cadherin, and β1-integrin, to modulate the host cytoskeleton via disruption of the epithelial cell polarity necessary for maintaining the infection, but how this leads to the development of the...
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