Article
The predictive potential of the sweat chloride test in cystic fibrosis patients with the G551D mutation.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Dec 2013
Seliger Verena I, Rodman David, Van Goor Fredrick, Schmelz Andreas, Mueller Peter
Abstract excerpt
BACKGROUND: Ivacaftor, a cystic fibrosis transmembrane regulator (CFTR) potentiator, decreased sweat chloride concentrations and improved clinical measures in cystic fibrosis (CF) patients with the G551D mutation. RESULTS: Sweat chloride measurements at day 15 had an overall positive predictive v...
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