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Article

PROP-1 gene mutations in a 63-year-old woman presenting with osteoporosis and hyperlipidaemia.

Hormones (Athens, Greece) - 1 Jan 2000

Andrikoula Maria, Sertedaki Amalia, Andrikoula Sofia, Dacou-Voutetakis Catherine, Tsatsoulis Agathocles

Abstract excerpt

PROP-1 gene mutations have been reported as a cause of combined pituitary hormone deficiency. Physical and hormonal phenotypes of affected individuals are variable. We report a 63-year-old female who presented with osteoporosis. She was short, did not enter puberty spontaneously and had primary amenorrhea. Biochemical evaluation revealed secondary hypothyroidism and mixed hyperlipidaemia, while dynamic testing of...

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PMID: 23624138
DOI: 10.1007/BF03401294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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