Article
Resistance to treatment in gastrointestinal stromal tumours: what radiologists should know.
Clinical radiology - 1 Aug 2013
Tirumani S H, Jagannathan J P, Hornick J L, Ramaiya N H
Abstract excerpt
Gastrointestinal stromal tumour resistance to treatment with imatinib occurs due to pre-existing or acquired mutations. Computed tomography and positron-emission tomography play an essential role in prompt recognition of resistance to treatment. Primary resistance to treatment, which is encountered in the first 6 months of treatment, is associated with specific mutations. Imaging of these tumours shows no...
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