Article
The type of mutations induced by carbon-ion-beam irradiation of the filamentous fungus Neurospora crassa.
Fungal biology - 1 Apr 2013
Ma Liqiu, Kazama Yusuke, Inoue Hirokazu, Abe Tomoko, Hatakeyama Shin, Tanaka Shuuitsu
Abstract excerpt
Heavy-ion beams are known to cause great damage to cellular components and are particularly renowned for their ability to generate DNA double-strand breaks (DSBs). To gain insight into the mutagenic effect of carbon-ion beams and how such damage is repaired by the cell, Neurospora crassa mutants deficient in one of three components involved in the repair of DSBs, nonhomologous end-joining (NHEJ), homologous...
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