Article
Quantum changes in Helicobacter pylori gene expression accompany host-adaptation.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Feb 2017
Chua Eng-Guan, Wise Michael J, Khosravi Yalda, Seow Shih-Wee, Amoyo Arlaine A, Pettersson Sven, Peters Fanny, Tay Chin-Yen, Perkins Timothy T, Loke Mun-Fai, Marshall Barry J, Vadivelu Jamuna
Abstract excerpt
Helicobacter pylori is a highly successful gastric pathogen. High genomic plasticity allows its adaptation to changing host environments. Complete genomes of H. pylori clinical isolate UM032 and its mice-adapted serial derivatives 298 and 299, generated using both PacBio RS and Illumina MiSeq sequencing technologies, were compared to identify novel elements responsible for host-adaptation. The acquisition of a...
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