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Article

Deep ion sequencing of amplicon adapter ligated libraries: a novel tool in molecular diagnostics of formalin fixed and paraffin embedded tissues.

Journal of clinical pathology - 1 Sept 2013

Becker Kerstin, Vollbrecht Claudia, Koitzsch Ulrike, Koenig Katharina, Fassunke Jana, Huss Sebastian, Nuernberg Peter, Heukamp Lukas C, Buettner Reinhard, Odenthal Margarete, Altmueller Janine, Merkelbach-Bruse Sabine

Abstract excerpt

Due to the advanced progress in personalised therapy concepts for non-small cell lung cancer (NSCLC), we applied the ion semiconductor sequencing (ISS) approach to molecular diagnosis of NSCLC, analysing a set of therapy relevant gene loci. DNA from macrodissected tumour samples of formalin fixed...

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Identifiers

PMID: 23618693
DOI: 10.1136/jclinpath-2013-201549

Genes

EGFR
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23618693-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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