Article
Complete genomic landscape of a recurring sporadic parathyroid carcinoma.
The Journal of pathology - 1 Jul 2013
Kasaian Katayoon, Wiseman Sam M, Thiessen Nina, Mungall Karen L, Corbett Richard D, Qian Jenny Q, Nip Ka Ming, He Ann, Tse Kane, Chuah Eric, Varhol Richard J, Pandoh Pawan, McDonald Helen, Zeng Thomas, Tam Angela, Schein Jacquie, Birol Inanc, Mungall Andrew J, Moore Richard A, Zhao Yongjun, Hirst Martin, Marra Marco A, Walker Blair A, Jones Steven J M
Abstract excerpt
Parathyroid carcinoma is a rare endocrine malignancy with an estimated incidence of less than 1 per million population. Excessive secretion of parathyroid hormone, extremely high serum calcium level, and the deleterious effects of hypercalcaemia are the clinical manifestations of the disease. Up to 60% of patients develop multiple disease recurrences and although long-term survival is possible with palliative...
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