Article
[New risk genes for Alzheimer's disease--biomarkers predicting the disease?].
Duodecim; laaketieteellinen aikakauskirja - 1 Jan 2013
Hiltunen Mikko, Haapasalo Annakaisa, Soininen Hilkka
Abstract excerpt
Genetic risk factors for Alzheimer's disease do not directly cause the disease, but instead increase the likelihood of developing it. Genetic identification of alterations in risk genes as such is not sufficient to elucidate their role in the pathogenesis of the disease. Additional functional investigations are required in which mechanisms of action of the risk genes are identified in events that are essential...
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