Article
Genomic analysis and reconstruction of cefotaxime resistance in Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy - 1 Aug 2013
Fani Fereshteh, Brotherton Marie-Christine, Leprohon Philippe, Ouellette Marc
Abstract excerpt
OBJECTIVES: To identify non-penicillin-binding protein (PBP) mutations contributing to resistance to the third-generation cephalosporin cefotaxime in Streptococcus pneumoniae at the genome-wide scale. METHODS: The genomes of two in vitro S. pneumoniae cefotaxime-resistant isolates and of two tran...
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