Article
Molecular variants of cholecystokinin after endogenous stimulation in humans: a time study.
The American journal of physiology - 1 Jun 1990
Eysselein V E, Eberlein G A, Hesse W H, Schaeffer M, Grandt D, Williams R, Goebell H, Reeve J R
Abstract excerpt
The time-dependent release of molecular variants of cholecystokinin (CCK) into the circulation was studied before and 1, 2, and 4 h after a test meal in six healthy volunteers. At each time period, 100 ml of blood were drawn in a manner to inhibit CCK degradation. Plasma was formed and CCK concentrated by Sep-Pak C18 cartridge chromatography. Molecular variants of CCK and gastrin were well separated from each...
Topics
- Animals
- Cholecystokinin
- Chromatography, High Pressure Liquid
- Dogs
- Genetic Variation
- Humans
- Intestinal Mucosa
- Intestine, Small