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Article

Endothelial nitric oxide synthase gene intron 4 polymorphism in non-traumatic osteonecrosis of the femoral head.

International orthopaedics - 1 Jul 2013

Gagala Jacek, Buraczynska Monika, Mazurkiewicz Tomasz, Ksiazek Andrzej

Abstract excerpt

PURPOSE: Nitric oxide (NO) synthesised by endothelial NO synthase (eNOS) is a potent regulator of internal haemodynamics. A polymorphism in intron 4 of the eNOS is associated with different vascular disorders. We investigated the potential involvement of this polymorphism in idiopathic and secondary osteonecrosis of the femoral head (ONFH) in Polish patients. METHODS: We performed a study involving 68 patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23604198
DOI: 10.1007/s00264-013-1892-7
PMCID: PMC3685672

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