Article
[Polymorphism of regulatory regions of growth factor gene of vascular endothelium VEGFA in breast cancer patients with family history].
Voprosy onkologii - 1 Jan 2012
Shevchenko A V, Konenkov V I, Garbukov E Iu, Stakheeva M N
Abstract excerpt
Analyzed the association of functional polymorphisms of VEGFA at positions -2578 of promoter region and at position +936 3' of untranslated region in a group of healthy women and breast cancer patients with the aim to detect informative markers associated with the risk of disease. The study included 395 DNA samples from women with breast cancer and 298 healthy women. Genotyping of polymorphisms of C-2578A and C...
Topics
- Adult
- Aged
- Aged, 80 and over
- Breast Neoplasms
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Middle Aged
- Odds Ratio
- Polymorphism, Restriction Fragment Length
