Article
Genetic variation in hypothalamic methyltrienolone (R1881) binding in male mice.
Physiology & behavior - 1 Mar 1990
Chen X A, Simon N G
Abstract excerpt
Methyltrienolone (R1881) binding to androgen receptors (AR) from combined hypothalamic-preoptic-septal cytosol was examined in CF-1, CFW, and CD-1 male mice, strains that differ in their sensitivity to the aggression-promoting property of this hormone. Both the affinity of R1881-AR binding and the number of binding sites (Bmax) significantly differed among the genotypes. The dissociation constant (Kd) was lower...
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