EPSILON: an eQTL prioritization framework using similarity measures derived from local networks.

Abstract excerpt

MOTIVATION: When genomic data are associated with gene expression data, the resulting expression quantitative trait loci (eQTL) will likely span multiple genes. eQTL prioritization techniques can be used to select the most likely causal gene affecting the expression of a target gene from a list of candidates. As an input, these techniques use physical interaction networks that often contain highly connected genes...

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