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Article

E148Q MEFV mutation carriage and longevity in individuals of Ashkenazi origin.

Immunologic research - 1 Jul 2013

Lidar Merav, Shinar Yael, Goldberg Marina, Ben-Zvi Ilan, Langevitz Pnina, Livneh Avi

Abstract excerpt

The high carriage rate of MEFV mutations in at risk populations suggests that they confer a selective advantage, possibly by way of protection from infections. Here, we sought to assess whether this putative protection contributes to longevity, by studying MEFV mutation status in nonagenarians and the association of mutation carriage with life-threatening conditions. DNA samples and a medical history...

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Source

Identifiers

PMID: 23592051
DOI: 10.1007/s12026-013-8414-y

Genes

MEFV

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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