Article
MEFV mutation carriage in Israeli Jewish individuals from ethnicities with low risk for familial Mediterranean fever.
Journal of human genetics - 1 Jun 2009
Feld Olga, Livneh Avi, Shinar Yael, Berkun Yaakov, Lidar Merav
Abstract excerpt
Familial Mediterranean fever (FMF) is a disease caused by mutations in the MEditerranean FeVer gene (MEFV), and in Israel it most commonly affects Jews of North African extraction, in whom the mutation carrier rate is as high as 1 in 5. To assess the protective as well as the modulating affect of MEFV mutation carriage on various inflammatory disease states, we sought to define the frequency of MEFV mutations in...
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