Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Peripheral Blood Mononuclear Cell Gene Expression in Chronic Obstructive Pulmonary Disease

23 May 2013

Abstract excerpt

Although most cases of chronic obstructive pulmonary disease (COPD) occur in smokers, only a fraction of smokers develop the disease. We hypothesized distinct molecular signatures for COPD and emphysema in the peripheral blood mononuclear cells (PBMCs) of current and former smokers. To test this hypothesis, we identified and validated PBMC gene expression profiles in smokers with and without COPD. We generated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Obstructive Pulmonary Disease (COPD) Research
Share to Neonatal Respiratory Health Research
Share to Pulmonary Hypertension Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23590301
DOI: 10.1165/rcmb.2012-0230oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Peripheral Blood Mononuclear Cell Gene Expression in Chronic Obstructive Pulmonary DiseasePMID 23590301Read ↗

Peripheral blood gene expression profiles in COPD subjectsSemantic proximity Read ↗

Meta-analysis of Gene Expression Microarray Datasets in Chronic Obstructive Pulmonary DiseaseSemantic proximity Read ↗

Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking.Semantic proximity Read ↗

DNA methylation profiling in peripheral lung tissues of smokers and patients with COPDSemantic proximity Read ↗

Transcriptional analysis identifies potential biomarkers and molecular regulators in pneumonia and COPD exacerbationSemantic proximity Read ↗

Identification of diagnostic biomarkers and immune cell profiles associated with COPD integrated bioinformatics and machine learningSemantic proximity Read ↗

Investigation of differential expression in phospholipid metabolism-related genes in bronchial epithelial cells of asthma patientsSemantic proximity Read ↗

Bioinformatics analysis of PLA2G7 as an immune-related biomarker in COPD by promoting expansion and suppressive functions of MDSCs.Semantic proximity Read ↗

Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma.Semantic proximity Read ↗

Screening of Lipid Metabolism-Related Genes as Diagnostic Indicators in Chronic Obstructive Pulmonary DiseaseSemantic proximity Read ↗

The Crucial Role of the PPAR Signaling Pathway in the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease: An Analysis of Gene Expression and Macrophage Polarization.Semantic proximity Read ↗

Novel computational analysis of large transcriptome datasets identifies sets of genes distinguishing chronic obstructive pulmonary disease from healthy lung samplesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.